Sure. But if you're going to be writing a ton of boilerplate code to get all your usual C++ libraries working in BlitzMAX, there's a certain point where you might as well write the whole thing in C++ anyway, or just skip right to C#.
True, however, my point was merely; that once it has a full deck of cards including 3D, most will never have to mess about as almost everything they will be included in the native stuff.