A program like 3DSMax will let you have lots of UV sets (although I can't really imagine using more than 1 or 2 for most things) and as many textures per-mesh as you can bothered to set up.
Don't know how many of each export formats such as 3DS or B3D support though, although I've used B3D meshes with 10 or so different materials (textures) on them in Blitz3D.
Don't know how many of each export formats such as 3DS or B3D support though, although I've used B3D meshes with 10 or so different materials (textures) on them in Blitz3D.