It depends on your hardware. I'm running Vista Home Premium on a E4300 (OC at 2,4GHz), 2 GB RAM and a GeForce 8800GTS and I have to say: I'd never go back to XP again. With Aero and the right hardware Vista feels more responsive. MacOSX is cool as well but you'll have headaches sometimes when your software just runs on Windows (especially games).
Honest opinions on Vista
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