Why would you want to? It's slow, it's expensive, and it doesn't offer any real advantage to the average user.
Anyway, the answer is likely no. I don't know how you expect a precise answer when you don't even tell anyone what motherboard you're trying to put it in, but most boards that don't require it, don't support it.
Anyway, the answer is likely no. I don't know how you expect a precise answer when you don't even tell anyone what motherboard you're trying to put it in, but most boards that don't require it, don't support it.