You'd be surprised how often those two things are mutually exclusive...
Tell me about it....everything looks fine in the good browsers, on IE, all horridly broken until you toss in a few little tweaks that doesn't affect the other browsers, but fixes it all in IE (well, sort of), and still passes validation.
(I use XHTML1.0 Strict here, so more of a PITA for me getting it right in IE)
Site looks fine here in Firefox, I'm also in the same boat as Noel regarding fonts, possibly use 1bit-transparent PNG/GIFs instead?
Also, one thing that's a bit of a niggle to me, is the right-column, the way you did the links, just, ugh, see here to find out why I do. It just looks less professional with the way it currently is imo.