Software to help prevent RSI

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Smoking works well... Get a 40 a day habbit. Once you're heavily addicted to them you'll need to keep leaving your desk and standing outside your office to have a smoke.

Therefore you get your rest breaks for both eyes and hands.

The downside of course is you'll probably die of cancer or a heart attack instead.

Of course this would work with any highly addictive drug, so you could use Crack cocaine or Heroin.

Disclaimer: This views expressed in the post are not serious.